paraneoplastic syndrome

The Clinical Analysis of Paraneoplastic Syndrome : 19 Cases

19例副肿瘤综合征患者临床分析

Analysing the Clinical Characteristics of Paraneoplastic Syndrome of Nervous System

神经系统副肿瘤综合征的临床表现分析

Clinical analysis of lung cancer with neurological paraneoplastic syndrome as initial symptom

以神经副癌综合征为首发症状的肺癌临床分析

Paraneoplastic syndrome , nervous system ; Lung neoplasms ; Diagnosis .

副肿瘤综合征，神经系统；肺肿瘤；诊断。

Study on Specific Neuron-antibody in Patients With Paraneoplastic Syndrome of Nervous System

神经系统副肿瘤性综合征患者体内特异性神经元抗体的研究

After treatment , most of the paraneoplastic syndrome disappeared or improved .

治疗后，大部分副癌综合征可缓解或消失。

She could also have paraneoplastic syndrome .

她也会有肾上腺综合症。

Clinical feature of abnormal glucose metabolism in the patients with paraneoplastic syndrome of primary hepatic carcinoma

原发性肝癌伴癌综合征患者糖代谢异常的临床特征

The Role of the Autoantibodies in Diagnosis of Neurological Paraneoplastic Syndrome

自身抗体对副肿瘤综合征诊断价值的探讨

Objective To investigate the clinical characteristics and diagnosis of lung cancer with paraneoplastic syndrome as initial symptom .

目的探讨以副癌综合征为首发症状的原发性肺癌的临床特征及诊断。

Objective : To increase the identification of leukemia related paraneoplastic syndrome and reduce the misdiagnosis .

目的：提高对白血病相关性副癌综合征的认识，减少临床漏诊、误诊。

Significance of anti-neuronal antibodies in the early diagnosis of paraneoplastic syndrome of nervous system ;

目的探讨检测特异性神经元抗体在诊断副肿瘤性神经系统疾病中的价值。

Conclusion It is helpful to the early diagnosis of lung cancer and it prognosis to realize paraneoplastic syndrome .

结论提高对副癌综合征的认识有助于肺癌的早期诊断，对预后估计也有一定帮助。

Objective To investigate the clinical characteristics of lung cancer with neurological paraneoplastic syndrome ( NPS ) as initial symptom .

肺癌的副癌综合征可在肺部症状出现之前、之后或同时出现。

Paraneoplastic Syndrome in Lung Cancer Analysis of 208 Cases of Clinical Imaging Clinical Imaging Analysis of 208 Cases with Paraneoplastic Syndrome in Lung Cancer

肺癌副癌综合征208例临床影像分析

Objective To study the significance of anti-neuronal antibodies in the early diagnosis of paraneoplastic syndrome of nervous system ( PNSNS ) .

目的探讨特异性抗神经元抗体对神经系统副肿瘤综合征（paraneoplasticsyndromeofnervoussystem，PNSNS）早期诊断的意义。

Results ① Among the patients with lung cancer in the hospital , 11.8 % ( 168 / 1 426 ) had paraneoplastic syndrome as initial symptom .

结果①副癌综合征为首发症状的原发性肺癌占同期肺癌住院人数的11.8%（168/1426），男女之比为4.25∶1。

Objective To investigate the clinic , electrophysiological , pathological characters of paraneoplastic syndrome which manifested with motor neurone disease-like .

目的探讨以运动神经元病为表现的副肿瘤综合征的临床、电生理学、病理学特点。

Objectives To explore the incidence rate of paraneoplastic syndrome of primary liver carcinoma , and the relationship with the size of tumor and the level of AFP .

目的探讨原发性肝癌伴癌综合征的发病率及与AFP水平和肿瘤体积大小的相关性。

Objective : To analyze the clinical feature of paraneoplastic syndrome of primary hepatic carcinoma and approach the alter rule in biochemistry and pathology parameter of paraneoplastic syndromes .

目的：分析原发性肝癌（primaryhepaticCarcinoma，PHC）伴癌综合征（Paraneoplasticsyndrome，PNS）的临床特征，探讨PNS患者生化及病理参数的改变规律。

Methods The clinical data of 168 cases of lung cancer with paraneoplastic syndrome as initial symptom were analysed from Jan. 1990 , to Nov. 2002 , in the hospital .

方法回顾分析本院自1990年1月至2002年11月间收治的168例副癌综合征为首发症状的原发性肺癌临床资料。

Dermatomyositis / Polymyositis associated with malignant tumor incidence is far higher than in other connective tissue diseases . It is recognized as a paraneoplastic syndrome in adults .

皮肌炎/多发性肌炎与恶性肿瘤的伴发率远高于其他结缔组织疾病，是副肿瘤性皮肤病之一。

Specific neuronal anti-Hu anti-body is a specific and sensitive marker in detecting paraneoplastic syndrome of nervous system ( PNSNS ) and play a important role in immune disorders ;

特异性神经元抗一Hu抗体是PNSNS的特异性、敏感性指标，推测在神经元的免疫损伤机制中具有重要作用。

Results Among the patients with lung cancer , 8.2 % manifest paraneoplastic syndrome as initial symptoms that are multifarious . The common symptoms consist of finger clubbing and disorder of nervous system .

结果以副癌综合征为首发症状的肺癌患者占同期住院肺癌患者的8.2%，副癌综合征表现多样，以杵状指、神经系统症状等较为多见。

It is proved that there is some certain relationship between HuD low expression and Hirschsprung disease . The polyclonal antibody , anti-Hu antibody , plays a role in pathogenesis of paraneoplastic syndrome and pseudo-intestinal obstruction .

现已证实，HuD的低表达与视神经发育障碍、先天性巨结肠等疾病相关，其多克隆抗体anti-Hu抗体在副肿瘤综合征、假性肠梗阻等多种疾病的发病机制中扮演一定角色。

Objective To examine the direct effects of the autoantibody ( anti-Hu antibody ) of paraneoplastic neurological syndrome on primary-cultured neurons .

目的研究副肿瘤综合征（PNS）自身抗体（抗Hu抗体）对培养神经细胞的直接影响。

The expression of the cancer-testis-brain antigens in tumors may be a mechanism that tumors break the patients ′ immune tolerance resulted in paraneoplastic neurological syndrome .

认识这些肿瘤睾丸脑抗原的意义在于它们在肿瘤组织的表达可能是肿瘤破坏机体免疫耐受的一种机制，其相关神经副肿瘤综合症可能是一些隐匿肿瘤的早期表现。

The nervous system damages caused by the tumor infiltration , metastasis and paraneoplastic neurological syndrome are difficult to distinguish from the other nervous system disease in clinical manifestations and are easily misdiagnosed , the doctor should be vigilant .

神经系统副肿瘤综合征和肿瘤浸润、转移或致代谢异常等所致神经系统损害，在临床表现上与其他原发神经系统疾病不易区分，容易误诊，应当提高警惕，注意鉴别。